In a patient with chronic renal failure undergoing a transplant, what complication relates to the immunosuppressive drug used?

Prepare for the NBME Form 26 Test. Study with flashcards and multiple choice questions, each question has hints and explanations. Get ready for your exam!

In transplant recipients, the use of immunosuppressive drugs is critical to prevent organ rejection but also increases the risk of various infections, particularly viral infections. Cytomegalovirus (CMV) infection is a well-known complication associated with the use of immunosuppressive therapy. These drugs, which include agents like corticosteroids, azathioprine, or tacrolimus, suppress the immune system, making the patient more vulnerable to opportunistic infections.

CMV is a common virus that can remain dormant in the body but may reactivate when the immune system is weakened. In the context of solid organ transplants, CMV infection can lead to significant morbidity, including pneumonitis, colitis, and even organ rejection in severe cases. Monitoring for CMV infection and managing it appropriately is an essential component of post-transplant care in patients receiving immunosuppressive therapy.

The other potential complications listed, such as hepatic necrosis, thromboembolic events, and acute renal failure, while they can occur in the context of various medical conditions or medications, are not as directly linked to the common immunosuppressive drugs used in transplant patients as CMV infection. Thus, the immunosuppressive therapy’s direct association with increased susceptibility to

Subscribe

Get the latest from Examzify

You can unsubscribe at any time. Read our privacy policy